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Another COVID-19 vaccine is almost ready to begin being distributed – a single-shot inoculation made by Johnson & Johnson’s Janssen pharmaceutical subsidiary. The company just released an efficacy report based on data from its Phase 3 trial, which found that the new vaccine is 66% effective overall in preventing moderate to severe incarnations of COVID-19 in those who received the jab, and 85% effective in preventing sever disease.
Those numbers aren’t as impressive as the reported figures for the Moderna and Pfizer/BioNTech vaccines that are already being distributed via emergency FDA approval, both of which reported 90+% efficacy. But Johnson & Johnson’s vaccine is a single shot rather than a two-course treatment, which should make it much easier to distribute much more quickly. The vaccine also showed 100% efficacy in preventing hospitalization or death among participants in the trial, 28 days after vaccination, which is a key measure when considering the broader impact of COVID-19 on healthcare resources, and efficacy varied by region, with the jab proving 72% effective in the U.S. across moderate and severe cases vs. 66% globally.
It’s also important to note that Johnson & Johnson’s Phase 3 trial is happening amid the emergence of new strains of the virus, including much more contagious versions like the UK and South African variants. At the time that both Moderna and BioNTech released their trial data, these variants hadn’t yet emerged or been confirmed by pandemic researchers.
Johnson & Johnson’s vaccine uses a modified version of a common cold virus to deliver DNA that provides a person’s body with instructions on building a replica of the spike protein that SARS-CoV-2 uses to attach to cells. The modified adenovirus can’t replicate in human cells, however, meaning it won’t lead to illness – only an immune response that can later be employed to combat contracting the virus that leads to COVID-19. This adenovirus method is much more proven in terms of use in human patients vs. the mRNA method that the other vaccines currently in use employ.
All of which is to say, despite headline numbers that appear to fall short relative to the data we’ve seen from Moderna and Pfizer, this Johnson & Johnson report is actually very encouraging. The company says it expects to file a request for an Emergency Use Approval (EUA) from the FDA in February, which could see it begin to be distributed next month, adding yet another weapon in the arsenal to combat the global pandemic.
Uber’s plan to acquire Autocab, a maker of SaaS for booking and dispatch software for the taxi and private hire vehicle industry which also operates a global trip marketplace for taxis and PHVs (iGo), is being looked at by the UK’s competition watchdog — which announced the launch of an inquiry today.
The deadline for a decision by the Competition and Markets Authority (CMA) on whether to refer the merger for an in-depth investigation is March 26.
Uber announced its intention to acquire UK-based Autocab last August.
Competition considerations could arise if Uber, a provider of ride-hailing services that competes with traditional taxis and private hire vehicle firms for customers, were to shutter Autocab’s alternative trip booking marketplace or close it in selective markets where its own ride-hailing service operates, for example.
Although, at the time it announced the acquisition, Uber said it planned to support Autocab’s expansion of SaaS and iGo internationally. The move also looks intended to create more opportunities for Uber drivers to pick up jobs from outside its own platform, including delivery work, as ride-hailing has faced a demand squeeze during the COVID-19 pandemic.
Nonetheless, the overlap between Autocab’s iGo marketplace and Uber’s core rides service certainly merits questions being asked about risks to competition.
The CMA has opened an invitation for comment on the merger — with a February 12 deadline for submissions.
“The CMA is considering whether it is or may be the case that this transaction, if carried into effect, will result in the creation of a relevant merger situation under the merger provisions of the Enterprise Act 2002 and, if so, whether the creation of that situation may be expected to result in a substantial lessening of competition within any market or markets in the United Kingdom for goods or services,” it writes, adding: “To assist it with this assessment, the CMA invites comments on the transaction from any interested party.”
Commenting on the inquiry in a statement, an Uber spokeswoman said: “We are cooperating fully with the UK Competition and Market Authority’s inquiry to ensure it can conclude its review as quickly as possible. We are confident that this acquisition is positive for consumers, will help local operators grow and provide drivers with genuine earning opportunities.”
This report was updated with Uber’s statement
Source: https://techcrunch.com/2021/01/29/ubers-autocab-acquisition-gets-eyed-by-uk-competition-watchdog/
Sirenum, a platform for remotely managing a shift-based workforce across industries such as railway, aviation, construction, and the gig economy, has raised a $2.7 million Series A funding round from new investors including former Tesco CEO Sir Terry Leahy, Intrinsic Capital founding partner Mark Horrocks and investment manager Bill Currie.
Sirenum says its subscription model platform simplifies the process of managing shift workers, including rostering and managing schedules, monitoring and engaging staff, and processing key financial processes including payroll. Its clients include Randstad, Impellam, Manpower and GI Group as well as specialist agencies like TES.
The issue with shift workers is that they need to be in the right place at the right time and paid the right amount. Obviously. Sirenum says it allows staff to manage their own time by accepting or rejecting shifts and check their payroll at any time through a mobile app. The platform handles shift management, payroll, compliance, and scheduling. The app also tracks the fatigue of workers based on the UK’s Health and Safety guidelines, meaning employers can track the wellness of employees and adhere to compliance.
The product came about when Sirenum founder Benjamin Rubin ran a staffing agency in London. He was on honeymoon with his wife when he received a call that one of his employees had been hit by a train.
Thankfully, the employee was fine, but Rubin realized that to avoid being in that same situation again, he needed a tool to be able to manage his staff safely at multiple locations. He developed the Sirenum product as a solution for his agency and in 2012 won the contract to staff the Olympic Stadium. In 2014 Sirenum became a standalone product. It now claims to have nearly 400,000 workers on the platform.
Its competitors include TempBuddy (owned by Bullhorn), Shiftboard, and WorkN. Shiftboard has raised $16.9 million to date.
French startup Chefclub announced earlier this week that it has raised a $17 million funding round led by First Bridge Ventures. SEB Alliance, the venture arm of kitchen appliance maker Groupe SEB, Korelya Capital and Algaé Ventures are also participating.
Chefclub has been building a major media brand on social media platforms. It has attracted a huge audience that doesn’t look bad next to well-funded media brands Tastemade and Tasty.
I already covered the company at length, so I encourage you to read my previous profile of the company:
Chefclub is an interesting lesson in sales funnel. It has a huge top of the funnel with 100 million followers YouTube, Snapchat, Instagram and TikTok. Overall, they generate over 1 billion views per month.
The company leverages that audience to create new products. It starts with cooking books, obviously. Chefclub has sold 700,000 books so far. As those books are self-published, the company gets to keep a good chunk of the revenue.
More recently, the startup has launched cooking kits for kids with colorful measuring cups, cooking accessories and easy-to-understand recipes. 150,000 people have bought a product for children.
Chefclub now wants to display its brands in stores thanks to partnerships. That’s why having Groupe SEB as an investor makes sense. You can imagine co-branded items boosted by promotion on Chefclub’s accounts.
Finally, the startup plans to enter a new market — consumer-packaged goods. That’s the same thinking behind it, except that we’re talking about food. It’s interesting to see that Chefclub doesn’t think online ads represent the future of the company. And it seems like a smart decision during the current economic crisis.
Xiaomi, the world’s third largest smartphone maker, today unveiled “Mi Air Charge Technology” that it says can deliver 5W power to multiple devices “within a radius of several metres” as the Chinese giant invited customers to a “true wireless charging era.”
The company said it has self-developed an isolated charging pile that has five phase interference antennas built-in, which can “accurately detect the location of the smartphone.”
A phase control array composed of 144 antennas transmits millimeter-wide waves directly to the phone through beamforming, the company said, adding that “in the near future” the system will also be able to work with smart watches, bracelets, and other wearable devices.
A company spokesperson said Xiaomi won’t be rolling out this system to consumer products this year.
Here’s how the company has described the mechanics of its new tech:
On the smartphone side, Xiaomi has also developed a miniaturized antenna array with built-in “beacon antenna” and “receiving antenna array”. Beacon antenna broadcasts position information with low power consumption. The receiving antenna array composed of 14 antennas converts the millimeter wave signal emitted by the charging pile into electric energy through the rectifier circuit, to turn the sci-fi charging experience into reality.
Currently, Xiaomi remote charging technology is capable of 5-watt remote charging for a single device within a radius of several meters. Apart from that, multiple devices can also be charged at the same time (each device supports 5 watts), and even physical obstacles do not reduce the charging efficiency.
